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DeCS
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Descriptor English:
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Receptors, Notch
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Descriptor Spanish:
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Receptores Notch
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Descriptor Portuguese:
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Receptores Notch
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Synonyms English:
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Notch Proteins
Notch Receptors
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Tree Number:
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D12.776.543.750.725
D12.776.930.770
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Definition English:
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A family of conserved cell surface receptors that contain EPIDERMAL GROWTH FACTOR repeats in their extracellular domain and ANKYRIN REPEATS in their cytoplasmic domains. The cytoplasmic domains are released upon ligand binding and translocate to the CELL NUCLEUS, where they act as transcription factors. |
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History Note English:
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2006(1990)
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Allowable Qualifiers English:
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Record Number:
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51148
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Unique Identifier:
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D051880
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Occurrence in VHL:
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Similar:
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DeCS
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